Hotels in Santee, South Carolina

  • Overview

    Santee is a small town located in the state of South Carolina in the United States. Nestled along the banks of Lake Marion, Santee offers a picturesque setting with its charming neighborhoods, beautiful scenery, and warm southern hospitality. The area is known for its rich history, outdoor recreational activities, and Southern cuisine.

  • When to visit

    The best time to visit Santee is during the spring and fall seasons when the weather is mild and comfortable for outdoor activities. The region experiences hot and humid summers, making it ideal for water sports and lake adventures. Winter can be chilly, but visitors can still enjoy the town's cozy atmosphere and participate in holiday events.

  • Reasons to Visit

    There are plenty of reasons to visit Santee. Nature enthusiasts will appreciate the abundance of outdoor activities available, including fishing, boating, hiking, and golf. History buffs can explore the nearby historic sites, such as the Santee Indian Mound and the Old Santee Canal State Park. Food lovers can indulge in delicious Southern cuisine at the local restaurants, which serve up mouth-watering dishes like barbecue and fried catfish.

  • Nearby Attractions

  • Santee Indian Mound

    The Santee Indian Mound is an archaeological site that offers a glimpse into the region's Native American history. Visitors can explore the preserved earthwork structure, which was used by indigenous peoples for ceremonial purposes.

  • Old Santee Canal State Park

    The Old Santee Canal State Park is a historical park that showcases the role of the canal system in 18th and 19th-century transportation. Visitors can learn about the engineering marvels of the early canals and enjoy activities like hiking, biking, and picnicking.

  • Lake Marion

    Lake Marion is a large freshwater lake renowned for its fishing opportunities. Anglers can try their luck at catching bass, crappie, and catfish. Boating and water sports are also popular on the lake, offering fun and relaxation for visitors.

  • Santee National Golf Club

    Golf enthusiasts will enjoy a round of golf at the Santee National Golf Club. This championship 18-hole golf course features beautiful fairways, challenging holes, and scenic views of the surrounding nature.

  • Hotels

  • Baymont by Wyndham Santee

    - Make yourself at home in one of the 60 air-conditioned rooms featuring refrigerators and microwaves. Complimentary wireless internet access keeps you connected, and cable programming is available for Next available price is 90.24 on Sept. 13, 2025. Baymont by Wyndham Santee

  • Best Western Plus Santee Inn

    - Make yourself at home in one of the 102 air-conditioned rooms featuring refrigerators and microwaves. Wireless internet access (surcharge) keeps you connected, and cable programming is available for y Next available price is 112.10 on Sept. 14, 2025. Best Western Plus Santee Inn

  • Comfort Inn & Suites Santee

    - Stay in one of 61 guestrooms featuring plasma televisions. Your pillowtop bed comes with Frette Italian sheets, and all rooms are furnished with sofa beds. Complimentary wireless internet access keeps Next available price is 148.71 on Sept. 13, 2025. Comfort Inn & Suites Santee

  • Econo Lodge

    - Make yourself at home in one of the 37 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available fo Next available price is 72.11 on Sept. 13, 2025. Econo Lodge

  • Fairfield Inn & Suites by Marriott Santee

    - Make yourself at home in one of the 91 guestrooms featuring refrigerators and flat-screen televisions. Rooms have private patios. Complimentary wireless internet access keeps you connected, and satell Next available price is 137.72 on Sept. 15, 2025. Fairfield Inn & Suites by Marriott Santee

  • Hampton Inn Santee-I-95

    - Make yourself at home in one of the 81 guestrooms featuring refrigerators and microwaves. 55-inch flat-screen televisions with satellite programming provide entertainment, while complimentary wireless Next available price is 175.75 on Sept. 13, 2025. Hampton Inn Santee-I-95

  • Holiday Inn Santee, an IHG Hotel

    - Make yourself at home in one of the 84 individually decorated guestrooms, featuring refrigerators and LED televisions. Complimentary wired and wireless internet access keeps you connected, and satelli Next available price is 161.87 on Sept. 13, 2025. Holiday Inn Santee, an IHG Hotel

  • Lake Marion Inn

    - Set in Santee, Lake Marion Inn offers a garden. There is a terrace and guests can make use of free WiFi and free private parking. Complete with a private bathroom fitted with a shower and free toilet Next available price is on . Lake Marion Inn

  • Red Roof Inn Santee

    - Make yourself at home in one of the 40 guestrooms featuring microwaves and flat-screen televisions. Complimentary wireless internet access keeps you connected, and satellite programming is available f Next available price is 69.34 on Sept. 15, 2025. Red Roof Inn Santee

  • Rodeway Inn Santee I-95

    - Located in Santee, Rodeway Inn Santee I-95 offers 2-star accommodation with a bar. Among the facilities of this property are a restaurant, a 24-hour front desk and an ATM, along with free WiFi through Next available price is on . Rodeway Inn Santee I-95

  • Rodeway Inn Santee I-95

    - Make yourself at home in one of the 105 air-conditioned rooms featuring refrigerators and flat-screen televisions. Your pillowtop bed comes with down comforters and Egyptian cotton sheets. Complimenta Next available price is 82.37 on Sept. 13, 2025. Rodeway Inn Santee I-95

  • Super 8 by Wyndham Santee

    - Make yourself at home in one of the 41 air-conditioned rooms featuring refrigerators and microwaves. Flat-screen televisions with satellite programming provide entertainment, while complimentary wirel Next available price is 90.37 on Sept. 13, 2025. Super 8 by Wyndham Santee

  • Travelodge by Wyndham Santee

    - Make yourself at home in one of the 34 guestrooms featuring refrigerators and microwaves. Complimentary wireless internet access keeps you connected, and cable programming is available for your entert Next available price is 66.50 on Sept. 13, 2025. Travelodge by Wyndham Santee
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13 hotels in Santee