Hotels in Florida Keys Scenic Highway, Monroe County

  • Overview

    The Florida Keys Scenic Highway is a breathtaking route that spans approximately 110 miles, connecting the mainland of Florida to the picturesque tropical islands of the Florida Keys. This highway offers a unique and stunning coastal drive, surrounded by crystal-clear turquoise waters and abundant natural beauty. It is a popular destination for travelers seeking a relaxing and adventurous escape.

  • When to visit

    The best time to visit the Florida Keys Scenic Highway is during the winter and spring months, from November to April. The weather is mild and enjoyable during this time, with temperatures ranging from the high 60s to low 80s Fahrenheit (15-27 degrees Celsius). It is the peak season, so expect more crowds, but you will also have access to a wider range of activities and events.

  • Reasons to Visit

    There are numerous reasons to visit the Florida Keys Scenic Highway. Nature enthusiasts can explore the fascinating underwater world by snorkeling or scuba diving in the vibrant coral reefs. Fishing enthusiasts can enjoy world-class fishing opportunities, with the chance to catch a variety of game fish. For those seeking relaxation, the idyllic beaches provide a perfect spot to unwind and soak up the sun. The Florida Keys are also known for their rich history, with charming towns and museums that offer insights into the region's past.

  • Nearby Attractions

  • John Pennekamp Coral Reef State Park

    One of the top attractions along the Florida Keys Scenic Highway, John Pennekamp Coral Reef State Park is a paradise for snorkelers and divers. It is home to the only living coral barrier reef in the continental United States, offering an incredible underwater world to explore.

  • Bahia Honda State Park

    Located on the stunning Bahia Honda Key, this state park features pristine beaches, crystal-clear waters, and lush tropical vegetation. Visitors can swim, sunbathe, kayak, and hike along the nature trails while enjoying the breathtaking views.

  • Key West

    Key West is the southernmost city in the United States and a vibrant hub of culture, history, and entertainment. It boasts colorful colonial architecture, lively nightlife, and famous landmarks such as the Ernest Hemingway Home and Museum.

  • Dolphin Research Center

    Situated on Grassy Key, the Dolphin Research Center offers a unique opportunity to interact with dolphins and learn about marine conservation. Visitors can participate in dolphin encounters, educational programs, and watch captivating dolphin shows.

  • Hotels

  • 1 Island Hideaway in the Keys

    - Make yourself comfortable in this individually decorated apartment, featuring a kitchen with a full-sized refrigerator/freezer and an oven. Your pillowtop bed comes with Egyptian cotton sheets. There' Next available price is on . 1 Island Hideaway in the Keys

  • Anchorage Resort & Yacht Club

    - Make yourself comfortable in this individually decorated apartment, featuring a kitchen with a full-sized refrigerator/freezer and a stovetop. There's a private balcony. Complimentary wireless interne Next available price is on . Anchorage Resort & Yacht Club

  • Bay Harbor Lodge

    - Make yourself at home in one of the 15 guestrooms featuring refrigerators and Smart televisions. Your memory foam bed comes with premium bedding. Complimentary wireless internet access keeps you conne Next available price is on . Bay Harbor Lodge

  • Brand New Key Largo Home

    - Make yourself at home in one of the 5 air-conditioned rooms featuring kitchens with full-sized refrigerators/freezers and ovens. Rooms have private patios. Flat-screen televisions with cable programmi Next available price is on . Brand New Key Largo Home

  • Breezy Palms Resort

    - Make yourself at home in one of the 40 guestrooms, featuring kitchens with full-sized refrigerators/freezers and microwaves. Complimentary wireless internet access keeps you connected, and cable progr Next available price is on . Breezy Palms Resort

  • Coco Plum Inn

    - Make yourself at home in one of the 14 air-conditioned rooms featuring refrigerators and microwaves. Complimentary wireless internet access keeps you connected, and cable programming is available for Next available price is on . Coco Plum Inn

  • Coconut Bay Resort Key Largo

    - Make yourself at home in one of the 6 air-conditioned rooms featuring refrigerators and microwaves. Flat-screen televisions with cable programming provide entertainment, while complimentary wireless i Next available price is on . Coconut Bay Resort Key Largo

  • Courtyard by Marriott Key West Waterfront

    - Make yourself at home in one of the 68 individually furnished guestrooms, featuring microwaves and LCD televisions. Rooms have private balconies or patios. Complimentary wired and wireless internet ac Next available price is 142.62 on Sept. 14, 2025. Courtyard by Marriott Key West Waterfront

  • Ed & Ellens Lodging Key largo

    - Make yourself at home in one of the 5 guestrooms, featuring kitchenettes with refrigerators and microwaves. Complimentary wireless internet access keeps you connected, and cable programming is availab Next available price is on . Ed & Ellens Lodging Key largo

  • Edgewater Lodge

    - Make yourself at home in one of the 16 individually decorated guestrooms, featuring microwaves and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable progra Next available price is on . Edgewater Lodge

  • Fiesta Key RV Resort

    - Make yourself at home in one of the 20 individually decorated guestrooms. Bathrooms have bathtubs or showers and complimentary toiletries. Conveniences include coffee/tea makers, and housekeeping is p Next available price is on . Fiesta Key RV Resort

  • Green world zone in Calusa

    - Green world zone in Calusa, a property with a terrace, is situated in Key Largo, 11 km from Pigeon Key, 26 km from Windley Key, as well as 32 km from Upper Matecumbe Key. This campground is 44 km from Next available price is on . Green world zone in Calusa

  • Hampton Inn Key Largo Manatee Bay

    - Make yourself at home in one of the 100 guestrooms featuring refrigerators and microwaves. Rooms have private balconies or patios. Wired and wireless internet access is complimentary, and LCD televisi Next available price is 151.05 on Sept. 14, 2025. Hampton Inn Key Largo Manatee Bay

  • JTs Key Largo Escape

    - Boasting air-conditioned accommodation with a balcony, JTs Key Largo Escape is situated in Jewfish. This property offers access to a terrace, free private parking and free WiFi. The property is non-sm Next available price is on . JTs Key Largo Escape

  • Key Largo Sound Vacations

    - Make yourself at home in one of the 2 air-conditioned rooms featuring kitchens with refrigerators and ovens. Rooms have private patios. Complimentary wireless internet access keeps you connected, and Next available price is on . Key Largo Sound Vacations

  • Kings Kamp

    - Stay in one of 12 guestrooms featuring flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Conveniences incl Next available price is on . Kings Kamp

  • Lime Tree Bay Resort

    - Make yourself at home in one of the 67 air-conditioned rooms featuring refrigerators and microwaves. Complimentary wireless internet access keeps you connected, and digital programming is available fo Next available price is 141.55 on Sept. 14, 2025. Lime Tree Bay Resort

  • Marina Del Mar Resort and Marina

    - Make yourself at home in one of the 76 air-conditioned rooms featuring refrigerators. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainm Next available price is 118.43 on Sept. 21, 2025. Marina Del Mar Resort and Marina

  • Moon Bay A410

    - Moon Bay A410 is set in Key Largo, 16 km from Pigeon Key, 31 km from Windley Key, as well as 36 km from Upper Matecumbe Key. Among the facilities at this property are a 24-hour front desk and a lift, Next available price is on . Moon Bay A410

  • Oceanfront w/ Dock & Kayak Pirate's Cove Key Largo

    - Oceanfront w/ Dock & Kayak Pirate's Cove Key Largo is a recently renovated holiday home in Jewfish, where guests can make the most of its outdoor swimming pool and garden. This beachfront property off Next available price is on . Oceanfront w/ Dock & Kayak Pirate's Cove Key Largo

  • Playa Largo Resort & Spa, Autograph Collection

    - Stay in one of 178 guestrooms featuring Smart televisions. Your pillowtop bed comes with down comforters and premium bedding. Complimentary wireless internet access keeps you connected, and cable prog Next available price is 265.05 on Sept. 14, 2025. Playa Largo Resort & Spa, Autograph Collection

  • Reefhouse Resort & Marina

    - Stay in one of 153 guestrooms featuring flat-screen televisions. Satellite television is provided for your entertainment. Bathrooms feature shower/tub combinations, complimentary toiletries, and hair Next available price is 237.95 on Sept. 14, 2025. Reefhouse Resort & Marina

  • Sands of Islamorada

    - Make yourself at home in one of the 9 individually decorated guestrooms, featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable prog Next available price is on . Sands of Islamorada

  • Sunkissed Vacation Rental

    - Situated in Key Largo and only 1.5 km from John Pennekamp State Park, Sunkissed Vacation Rental features accommodation with sea views, free WiFi and free private parking. This holiday home provides ai Next available price is on . Sunkissed Vacation Rental

  • Sunset Cove Beach Resort

    - Make yourself at home in one of the 25 air-conditioned rooms featuring microwaves. Complimentary wireless internet access is available to keep you connected. Bathrooms with showers are provided. Conve Next available price is on . Sunset Cove Beach Resort

  • Sunshine Key RV Resort & Marina

    - Treat yourself to a stay in one of the 10 individually decorated guestrooms, featuring fireplaces. Kitchens are outfitted with refrigerators, ovens, and stovetops. Cable television is provided for you Next available price is on . Sunshine Key RV Resort & Marina

  • Tiny House RV, Kayak

    - Set in Key Largo in the Florida region and John Pennekamp State Park reachable within 2.8 km, Tiny House RV, Kayak offers accommodation with free WiFi, barbecue facilities, a private beach area and fr Next available price is on . Tiny House RV, Kayak
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27 hotels in Florida Keys Scenic Highway