Hotels in Pemiscot County, Missouri

  • Overview

    Pemiscot County is a county located in the southeastern corner of the state of Missouri, United States. It is known for its picturesque landscapes and charming small-town atmosphere. The county is primarily rural, with vast stretches of fertile farmland, beautiful forests, and serene waterways, offering visitors a peaceful retreat away from the hustle and bustle of city life.

  • When to visit

    The best time to visit Pemiscot County is during the mild spring and fall seasons when temperatures are pleasant, and nature is at its vibrant best. During these times, you can explore the county's outdoor attractions comfortably and enjoy the picturesque landscapes without extreme heat or cold.

  • Reasons to Visit

    Pemiscot County offers a variety of attractions and activities for visitors to enjoy. Whether you are a nature lover, history enthusiast, or someone looking for a tranquil getaway, there is something for everyone. The county is home to several stunning nature reserves, where you can hike through picturesque trails, spot diverse wildlife, and enjoy breathtaking views. History buffs can explore the county's fascinating historical sites, including historic buildings and museums that showcase the rich heritage of the region.

  • Nearby Attractions

  • Lake Wappapello State Park

    Lake Wappapello State Park is a scenic park located on the shores of Lake Wappapello. It offers a wide range of recreational activities such as fishing, boating, camping, and hiking. The park is also home to an abundance of wildlife, making it a popular spot for nature enthusiasts.
  • Historic Hayti Depot

    The Historic Hayti Depot is a beautifully restored train station that now serves as a museum and visitor center. It showcases the history of Hayti and Pemiscot County through exhibits, artifacts, and photographs. Visitors can learn about the region's railroad heritage and its impact on the local community.
  • Mississippi River

    Pemiscot County is bordered by the mighty Mississippi River, providing breathtaking scenic views and numerous recreational opportunities. Visitors can enjoy fishing, boating, or simply relax by the riverbanks while taking in the tranquil ambiance.
  • Hotels

  • Drury Inn & Suites Hayti Caruthersville

    - Make yourself at home in one of the 99 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access kee Next available price is on . Drury Inn & Suites Hayti Caruthersville
  • Quality Inn Hayti North

    - Make yourself at home in one of the 47 guestrooms featuring refrigerators and microwaves. Complimentary wireless internet access keeps you connected, and cable programming is available for your entert Next available price is 94.05 on Sept. 16, 2025. Quality Inn Hayti North
  • Regency Travel Inn

    - Regency Travel Inn is located in Hayti. The 2-star hotel has air-conditioned rooms with a private bathroom and free WiFi. The hotel features family rooms. All units in the hotel are equipped with a T Next available price is on . Regency Travel Inn
  • The Farmstead Hotel

    - Make yourself at home in one of the 36 air-conditioned rooms featuring iPod docking stations and flat-screen televisions. Your pillowtop bed comes with down comforters and premium bedding. Complimenta Next available price is on . The Farmstead Hotel

4 hotels in Pemiscot County