Hotels in Mayo, Cowpens

  • Overview

    Mayo is a small town located in South Carolina, United States of America. It is known for its charming rural setting and warm hospitality. The town offers a peaceful and relaxed atmosphere, making it an ideal destination for those seeking a quiet getaway.

  • When to visit

    The best time to visit Mayo is during the spring and fall seasons. The weather during these times is mild and pleasant, perfect for outdoor activities. Spring brings blooming flowers and vibrant colors to the landscape, while fall offers stunning foliage and cooler temperatures.

  • Reasons to Visit

    There are several reasons to visit Mayo. One of the main attractions of this area is its natural beauty. The town is surrounded by picturesque countryside, with rolling hills and lush green fields. Visitors can enjoy scenic drives, hiking trails, and nature walks in the nearby parks and nature reserves. Mayo is also home to several quaint shops and local restaurants, where visitors can experience authentic Southern cuisine and shop for unique handmade crafts and antiques.

  • Nearby Attractions

  • Mayo Nature Reserve

    Mayo Nature Reserve is a tranquil park with scenic hiking trails, picnic areas, and a serene lake. It is an ideal destination for nature lovers and those looking to relax and unwind in a peaceful environment.
  • Main Street Shops

    Main Street is lined with charming shops and boutiques offering a variety of products, including local arts and crafts, clothing, and antiques. Visitors can enjoy a leisurely stroll along the street and browse through the unique and one-of-a-kind items.
  • Southern Comfort Restaurant

    Southern Comfort Restaurant is a popular local eatery known for its delicious Southern cuisine. Visitors can indulge in dishes such as fried chicken, collard greens, and cornbread, all served with a side of Southern hospitality.
  • Hotels

  • Hampton Inn Spartanburg-North I-85

    - Make yourself at home in one of the 86 guestrooms featuring refrigerators and microwaves. Your room comes with a pillowtop bed. 37-inch flat-screen televisions with cable programming provide entertain Next available price is 106.40 on Sept. 17, 2025. Hampton Inn Spartanburg-North I-85
  • Holiday Inn Express Hotel & Suites Spartanburg-North, an IHG Hotel

    - Make yourself at home in one of the 91 guestrooms featuring refrigerators and microwaves. Wired and wireless internet access is complimentary, while 32-inch LCD televisions with cable programming prov Next available price is 130.37 on Sept. 16, 2025. Holiday Inn Express Hotel & Suites Spartanburg-North, an IHG Hotel
  • Red Roof Inn Spartanburg - I-85

    - Stay in one of 111 guestrooms featuring flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Conveniences inc Next available price is on . Red Roof Inn Spartanburg - I-85

3 hotels in Mayo