Hotels in Lyon, Coahoma County

  • Overview

    Lyon is a charming town located in northern Mississippi, United States. Nestled in the heart of the Mississippi Delta, Lyon offers visitors a quintessential Southern experience with its warm hospitality and rich history. This rural town is surrounded by picturesque farmlands and sprawling cotton fields, creating a serene and peaceful atmosphere for visitors to enjoy.

  • When to visit

    The best time to visit Lyon is during the spring and fall seasons when the weather is pleasant and mild. Spring brings beautiful blooming flowers and lush greenery, while fall showcases vibrant foliage colors. However, Lyon offers its own charm throughout the year, and each season brings its own unique attractions and events.

  • Reasons to Visit

    There are several reasons to visit Lyon. History enthusiasts will appreciate the town's historical significance as the birthplace of legendary blues musician, Muddy Waters. Lyon is also known for its vibrant music scene, with live performances and festivals throughout the year. Nature lovers can explore the nearby Mississippi River and enjoy various outdoor activities like fishing and boating. Additionally, Lyon is home to a variety of charming local shops and restaurants, where visitors can indulge in delicious Southern cuisine and shop for unique handmade crafts.

  • Nearby Attractions

  • Muddy Waters' Birthplace

    Pay a visit to the birthplace of Muddy Waters, one of the most influential blues musicians in history. Explore the small museum dedicated to his life and career, and learn about the roots of blues music in the Mississippi Delta.

  • Mississippi River

    Take a leisurely stroll along the banks of the mighty Mississippi River, one of America's most iconic waterways. Enjoy stunning views, go fishing, or hop on a boat tour for a scenic ride along the river.

  • Local Music Festivals

    Experience the lively music scene in Lyon by attending one of the local music festivals that take place throughout the year. From blues and jazz to country and rock, there's something for every music lover to enjoy.

  • Antique Shops and Art Galleries

    Explore Lyon's charming downtown area, filled with antique shops and art galleries. Browse through a wide range of unique vintage items, collectibles, and locally crafted artworks, perfect for finding a special keepsake or a gift.

  • Hotels

  • Auberge Clarksdale Blues Hostel

    - Make yourself at home in one of the 6 air-conditioned guestrooms. Your room comes with a memory foam bed. Complimentary wireless internet access is available to keep you connected. Bathrooms with show Next available price is on . Auberge Clarksdale Blues Hostel

  • Clark House Inn

    - Clark House Inn in Clarksdale provides adults-only accommodation with a garden and a shared lounge. The bed and breakfast offers rooms with air conditioning, free private parking and free WiFi. At th Next available price is on . Clark House Inn

  • Hampton Inn Clarksdale

    - Make yourself at home in one of the 63 guestrooms featuring refrigerators and microwaves. Wired and wireless internet access is complimentary, while 42-inch LCD televisions with premium TV channels pr Next available price is on . Hampton Inn Clarksdale

  • High Cotton Condos

    - Make yourself at home in one of the 4 air-conditioned rooms featuring kitchens with full-sized refrigerators/freezers and stovetops. Complimentary wireless internet access keeps you connected, and fla Next available price is on . High Cotton Condos

  • Quality Inn

    - Make yourself at home in one of the 74 air-conditioned rooms featuring refrigerators and microwaves. Wireless internet access (surcharge) keeps you connected, and cable programming is available for yo Next available price is 89.29 on Sept. 19, 2025. Quality Inn

  • The Holy Moly Blues Central

    - Make yourself at home in one of the individually decorated guestrooms, featuring kitchens with full-sized refrigerators/freezers and stovetops. Flat-screen televisions with digital programming provide Next available price is on . The Holy Moly Blues Central

  • The Lofts at the Five & DIme

    - The Lofts at the Five & DIme provides air-conditioned rooms in Clarksdale. Both free WiFi and parking on-site are available at the aparthotel free of charge. The aparthotel features family rooms. Eac Next available price is on . The Lofts at the Five & DIme
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7 hotels in Lyon